D-Mannose is a naturally occurring monosaccharide or a simple sugar. It is a sweet substance that is  60% as sweet as sucrose yet it is low calorie [*]. 

The word “mannose” comes from a biblical term manna. In the Bible, manna is a sweet substance given to the Israelites during their journey in the Sinai Peninsula [*]. 

D-Mannose is important in human metabolism, and it has been cited as having a variety of positive physiological effects. It is beneficial to the immune system, as well as metabolic disorders, intestinal diseases, and urinary tract infections [****]. 

This compound is naturally produced in the human body, as well as plants [*]. Natural sources include cranberries, coffee, jujube, mango, apples, oranges, peaches, pu-erh tea, aloe vera, and seaweeds [*].

D-Mannose  is widely used in food, medicine, cosmetic, food-additive, and supplement industries [*]  As a dietary supplement, D-Mannose is used to support a healthy urinary tract, bladder and immune system.

The popularity of D-Mannose has led to hundreds of brands flooding the marketplace; however not all supplements are created equal! Unfortunately, more than 90% of D-Mannose supplements in the market simply DON’T WORK!

We understand the challenges in finding the right supplement for your health needs. That’s why we gathered years of research and made this guide to help you find the top-rated formulas that work for you.

Things To Be Cautious About

Has your brand been third-party tested? You should never buy supplements that don’t have Certificate of Analysis. The studies should be conducted in labs that are not affiliated with the manufacturer. These labs verify the product for safety and potency.

Does your d-mannose contain cheap synthetic fillers? Some brands add artificial fillers to cut cost to offer cheap products. Some of these cheap fillers we found were titanium dioxide and artificial coloring. You should never purchase cheap products when it comes to supplements.

No return policy or customer service – A reputable supplement company will offer 100% money-back guarantee policy and provide customer support through phone number and email. We noticed many formulas out there are just copies of the top-rated brands. They don’t offer an easy refund policy or don’t even have a phone number to prove they are real.

Top 5 D-Mannose Supplements

The result: we reviewed over 100+ brands of D-Mannose Supplements in the market and complied a list of top 5 formulas based on effectiveness, safety, pricing, return policy, and overall customer satisfaction.

1. Swanson D-Mannose

  • Shipping & Return Policy 98% 98%
  • Customer Service 96% 96%
  • Essential Ingredients 97% 97%
  • Effectiveness 97% 97%

Note: we test purchased this product. We can confirm on-time delivery, reliability and quality product from this brand.

*Individual Results May Vary – Ratings are based on Society Health Ranking System and do not necessarily reflect typical results from the use of these products. We encourage consumers to research by visiting each product websites for more information.

2. Solaray D-Mannose

  • Shipping & Return Policy 98% 98%
  • Customer Service 94% 94%
  • Essential Ingredients 97% 97%
  • Effectiveness 95% 95%

Note: we test purchased this product. We can confirm on-time delivery, reliability and quality product from this brand.

*Individual Results May Vary – Ratings are based on Society Health Ranking System and do not necessarily reflect typical results from the use of these products. We encourage consumers to research by visiting each product websites for more information.

3. Spring Valley D-Mannose

  • Shipping & Return Policy 95% 95%
  • Customer Service 94% 94%
  • Essential Ingredients 97% 97%
  • Effectiveness 94% 94%

Note: we test purchased this product. We can confirm on-time delivery, reliability and quality product from this brand.

*Individual Results May Vary – Ratings are based on Society Health Ranking System and do not necessarily reflect typical results from the use of these products. We encourage consumers to research by visiting each product websites for more information.

4. Now D-Mannose

  • Shipping & Return Policy 95% 95%
  • Customer Service 92% 92%
  • Essential Ingredients 97% 97%
  • Effectiveness 94% 94%

Note: we test purchased this product. We can confirm on-time delivery, reliability and quality product from this brand.

*Individual Results May Vary – Ratings are based on Society Health Ranking System and do not necessarily reflect typical results from the use of these products. We encourage consumers to research by visiting each product websites for more information.

5. BulkSupplements D-Mannose

  • Shipping & Return Policy 95% 95%
  • Customer Service 92% 92%
  • Essential Ingredients 96% 96%
  • Effectiveness 93% 93%

Note: we test purchased this product. We can confirm on-time delivery, reliability and quality product from this brand.

*Individual Results May Vary – Ratings are based on Society Health Ranking System and do not necessarily reflect typical results from the use of these products. We encourage consumers to research by visiting each product websites for more information.

Ranking Factors

Shipping & Return Policy: we check the shipping and return policy of each recommended product to make sure these brands stand behind their products.

Customer Service: we contact the top rated brands through email, chat or phone to make sure they are responsive and can answer potential questions customers might have.

Essential Ingredients: we verify the ingredients in every top rated brands, their safety and dosage amount in comparison with the latest scientific studies.

Overall Effectiveness: we check with real customers through their reviews and testimonials to make sure the top brands are as effective as they claim to be. We recommend the top 5 formulas based on their average score.

We highly recommend our reader to do their own research, read real reviews and contact any brands directly to make sure they can provide the products and services based on their needs.

1. Swanson D-Mannose

  • Shipping & Return Policy 98% 98%
  • Customer Service 96% 96%
  • Essential Ingredients 97% 97%
  • Effectiveness 97% 97%

*This is a subjective assessment based on the strength of the available information and our independent research and customer feedback. Results may vary based on individual.

Disclosure of Material Connection: we only recommend products and services which we believe will add value to the users. However, you should assume the owner of this website and/or blog has an affiliate relationship and/or another material connection, to any suppliers of goods and services that may be discussed here and may be compensated for showing ads or recommending products or services or linking to the supplier’s website.

Sources and Citations

1. d-Mannose: Properties, Production, and Applications: An Overview https://pubmed.ncbi.nlm.nih.gov/33401842/
2. Recent studies on the biological production of D-mannose https://pubmed.ncbi.nlm.nih.gov/31637494/
3. D-mannose: a promising support for acute urinary tract infections in women. A pilot study https://pubmed.ncbi.nlm.nih.gov/27424995/
4. Role of D-Mannose in the Prevention of Recurrent Urinary Tract Infections: Evidence from a Systematic Review of the Literature https://pubmed.ncbi.nlm.nih.gov/32972899/
5. d-Mannose: Properties, Production, and Applications: An Overview https://ift.onlinelibrary.wiley.com/doi/10.1111/1541-4337.12211