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Top 5 Probiotics with Pre & Post-biotic – How To Choose & What To Avoid (May 2024)

Probiotics are live bacteria that help keep your digestive system healthy. The colony of microorganisms in the body is essential in maintaining physiological processes, most notably the conversion of food to essential nutrients and transport of nutrients in the body. (Sources 1,4,7)

Before we delve into sources of probiotics and their associated health benefits, let’s understand what they are, how they function, and the mechanism in which they influence other functions in the body. (Sources 2,3)

The popularity of probiotics has led to hundreds of brands flooding the marketplace; however not all supplements are created equal! We examine a number of different factors:

  • Essential Ingredients
  • Label Accuracy
  • Potential Results
  • Product Safety
  • Consumer Reviews & Feedback
  • Refund & Return Policy

7 Things To Consider Before Buying

1. PRO-biotics with High CFU Count: choose a probiotic brand that has a higher number of probiotics, from at least 40 billion to 75 billion per serving. (Source 1)

2. PRE-biotics: to support the growth of probiotics once they get into your system, it is essential that prebiotics are also included in the formula. (Sources 1,2)

3. POST-biotics: are bioactive compounds made when the healthy bacteria in your gut ferment fiber. Many of the health benefits linked with prebiotics and probiotics actually come from the production of postbiotics. So it’s important for your supplement to include CoreBiome or other types of postbiotics. (Source 11)

4. Strain Diversity: choose a probiotic supplement that has at least 15 or more probiotic strains, such as Bacillus coagulans, Lactobacillus acidophilus, Bifidobacterium and Streptococcus thermophilus strains. (Sources 3,8,9)

5. Survivability: look for formulas that are in delayed release capsules such as DRcaps that protects the probiotics from stomach acid; or at least have MAKTrek in their formula. (Sources 2,3)

6. Be Shelf-Stable No Refrigeration Needed: make sure your probiotic supplement has soil-based probiotics and is shelf-stable, meaning it doesn’t need to be refrigerated. Ideally you want your probiotic to have a shelf-life of 2 years. (Sources 10,11)

7. Easy Refund Policy: it is important for a brand to offer a long refund policy. Many probiotic supplements may take up to three months to show their full benefits.  We highly recommend choosing a brand that offers a 90 days easy refund policy.

4 Things To Avoid

IMPORTANT: Has your brand been third-party tested? You should never buy supplements that don’t have Certificate of Analysis. The studies should be conducted in labs that are not affiliated with the manufacturer. These labs verify the product for safety and potency. It’s best to avoid products that don’t share their results. IMPORTANT
 
Does your supplement contain cheap synthetic fillers?
Some brands add artificial fillers to cut cost to offer cheap products. Some of these cheap fillers we found were additives and artificial coloring. You should never purchase cheap products when it comes to supplements.
 
No return policy or customer service
A reputable supplement company will offer 100% money-back guarantee policy and provide customer support through phone number and email. We noticed many formulas out there are just copies of the top-rated brands. They don’t offer an easy refund policy or don’t even have a phone number to prove they are real.
 
Avoid Subscription Auto-Billing Offers –  unfortunately many brands use this trick to charge your card without your authorization, even if a customer returns the product. One trick is they charge your card even 6 months after you made your initial purchases, which most people forgot about it. If you’re happy with the service, then it’s best to make another purchase in the future.

The result: There are many probiotics supplements in the market. To hep you choose, we purchased and reviewed 127+ supplements and compiled a list of our 5 picks based on their ingredients, label accuracy, pricing, return policy, and overall customer satisfaction. *

Top 5 Probiotic Supplements

#1 Gives Biome 100

Biome 100 Advance Probiotics contains 50 Billion CFU live cultures probiotics consisting of 18 diverse strains, plus NutraFlora® prebiotic and CoreBiome® Tributyrin postbiotic; with no synthetic fillers or additives and vegan-friendly.

Biome 100 is one of the few doctor formulated probiotics on the market with DRcaps™ delivery system to help protect your ingredients from stomach acid. It is also shelf-stable meaning it does NOT require refrigeration and has 2 years shelf life (most other brands have 1 year or less). We highly recommend this formula.

Biome 100 is made in USA, 3rd party lab tested for purity and label accuracy; a robust and advance formula. All purchases from Gives Nutrition are backed by 90 days 100% refund policy.

  • Form: Capsule
  • Dose: 1 capsule per day
  • Active ingredients: Probiotics, Prebiotic and Postbiotic
  • Number of servings: 30 per container
  • Shipping: free shipping on all orders
  • Refund Policy: 90 days full refund

See The Full Review

Results are based on user-generated experiences with these products, and individual results may vary. Please refer to the manufacturer’s product website for detailed information.

#2 MegaFlora

MegaFood MegaFlora is another great option. It contains 50 billion CFU probiotics from 14 different strains.

It also contains prebiotics, however it does not contain any postbiotics. This formula doesn’t contain any unnecessary additives and does not require refrigeration as well.

Made in the USA with all-natural, fast dissolving veggie capsule and 3rd Party Tested. All purchases from MegaFood are backed by 30 days return policy.

  • Form: Capsule
  • Dose: 2 capsules 
  • Active ingredients: Probiotics, Prebiotic, Turmeric
  • Number of servings: 45 per container
  • Return Policy: Limited 30 days

Learn More

Results are based on user-generated experiences with these products, and individual results may vary. Please refer to the manufacturer’s product website for detailed information.

#3 All Flora Probiotic

New Chapter All Flora Probiotic came in as our 3rd choice for probiotics. It’s no wonder because All Flora is a great product with 10 Billions CFUs from 2 different strains of probiotics.

Although some of the ingredients may be considered a type of prebiotic, however it doesn’t contain any NutraFlora and other kinds of postbiotics. Nevertheless, All Flora is a good choice for people that look for a simple probiotics supplement. It is made in the USA with all-natural, fast dissolving veggie capsule and 3rd Party Lab Tested. All purchases from New Chapter are backed by 30 days return policy.

  • Form: Capsule
  • Dose: 1 capsule 
  • Active ingredients: Probiotics, Prebiotic, Turmeric
  • Number of servings: 30 per container
  • Return Policy: 30 days

Learn More

Results are based on user-generated experiences with these products, and individual results may vary. Please refer to the manufacturer’s product website for detailed information.

#4 FloraMend

Thorne FloraMend Prime Probiotic is another top rated formula. Thorne offers a wide variety of supplements and their probiotics is another great choice for many consumers.

This formula contains 5 Billion CFU live culture probiotics from three different strains of probiotics.  Although this formla doesn’t contain any prebiotics or post-biotic, it’s another great choice for people looking for a lower dosage and simple formula.

FloraMend is also made in USA, shelf-stable and 3rd party lab tested for label accuracy and purity. All purchases from Thorne are backed by 60 days return policy.

  • Form: Capsules
  • Dose: 1 capsule
  • Active ingredients: blend of probiotics
  • Number of servings: 30 per container
  • Return Policy: 60 days limited

Learn More

Results are based on user-generated experiences with these products, and individual results may vary. Please refer to the manufacturer’s product website for detailed information.

#5 Tri-Butyrin Supreme

Designs for Health offers a wide variety of supplements. Their postbiotic supplement is a top rated brand for people looking for just a postbiotic formula.  It contains 300mg of CoreBiome Tributyrin.  This formula doesn’t contain any other strains of probiotics or prebiotics.

Tri-Butyrin Supreme is also made in USA, shelf-stable and 3rd party lab tested for label accuracy and purity. All purchases from Designs for Health are backed by 30 days return policy.

  • Form: Softgel
  • Dose: 2 capsules
  • Active ingredients: Tributyrin postbiotic
  • Number of servings: 30 per container
  • Return Policy: 30 days limited

Learn More

Results are based on user-generated experiences with these products, and individual results may vary. Please refer to the manufacturer’s product website for detailed information.

Contact Us:

If you have any questions please don’t hesitate to contact us. We would love to review different brands and feature more top formulas. We are open to any recommendations on how to make our site experience better. The more brands and formulas we review, the better we can serve you.

Unfortunately, some brands don’t like to be reviewed or featured; they use scare tactics and legal notices to be removed from our database.

societyhealthorg@gmail.com

If you’re a brand owner and wish to be removed from our database, contact us using the email address above.

Our Quality Brand [1]

#1 Gives Biome 100

Biome 100 Advance Probiotics contains 50 Billion CFU live cultures probiotics consisting of 18 diverse strains, plus NutraFlora® prebiotic and CoreBiome® Tributyrin postbiotic; with no synthetic fillers or additives and vegan-friendly.

Biome 100 is one of the few doctor formulated probiotics on the market with DRcaps™ delivery system to help protect your ingredients from stomach acid. It is also shelf-stable meaning it does NOT require refrigeration and has 2 years shelf life (most other brands have 1 year or less). We highly recommend this formula.

Biome 100 is made in USA, 3rd party lab tested for purity and label accuracy; a robust and advance formula. All purchases from Gives Nutrition are backed by 90 days 100% refund policy.

  • Form: Capsule
  • Dose: 1 capsule per day
  • Active ingredients: Probiotics, Prebiotic and Postbiotic
  • Number of servings: 30 per container
  • Shipping: free shipping on all orders
  • Refund Policy: 90 days full refund

See The Full Review

Results are based on user-generated experiences with these products, and individual results may vary. Please refer to the manufacturer’s product website for detailed information.

Sources & Citations

1. Degnan, F.H. (2008, February 1). The US Food and Drug Administration and Probiotics: Regulatory Categorization. OUP Academic. https://doi.org/10.1086/523324

2. A systematic review of the safety of probiotics – PubMed. (2014, February 1).PubMed. https://doi.org/10.1517/14740338.2014.872627

3. T. (2018,May 24). Probiotics: A Brief Guide. Love Bug Probiotics USA. https://lovebugprobiotics.com/blogs/news/probiotics-a-brief-guide

4. No evidence of harms of probiotic Lactobacillus rhamnosus GG ATCC 53103 in healthy elderly-a phase I open label study to assess safety, tolerability and cytokine responses – PubMed.(2014, December 1). PubMed. https://doi.org/10.1371/journal.pone.0113456

5. The efficacy of probiotics … of irritable bowel syndrome: a systematic review – PubMed. (2010, March 1).PubMed. https://doi.org/10.1136/gut.2008.167270

6. Safety assessment of probiotics for human use – PubMed. (2010, June 1). PubMed. https://doi.org/10.4161/gmic.1.3.12127

7. AmericanCollege of Gastroenterology monograph on the management of irritable bowel syndrome … constipation – PubMed. (2014, August 1). PubMed. https://doi.org/10.1038/ajg.2014.187

8. Probiotics for the prevention of … diarrhea in adults and children – PubMed. (2017,December 19). PubMed. https://doi.org/10.1002/14651858.CD006095.pub4

9. World Gastroenterology Organisation Global Guidelines: probiotics and prebiotics October 2011 – PubMed. (2012, July 1). PubMed. https://doi.org/10.1097/MCG.0b013e3182549092

10. Probioticsfor the …-associated diarrhea: a systematic review and meta-analysis – PubMed.(2012, May 9). PubMed. https://doi.org/10.1001/jama.2012.3507

11. Safetyof probiotics used to reduce risk and prevent … – PubMed. (2011, April 1). PubMed. https://pubmed.ncbi.nlm.nih.gov/23126627/

12. Dunnigan,A. P. (1936, January 1). Factors affecting the growth and viability of Lactobacillus acidophilus. Factors Affecting the Growth and Viability of Lactobacillus Acidophilus. https://drum.lib.umd.edu/items/d4ed8a91-2e94-424f-b398-5ab08494a416